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 Post subject: Pharmaceutical Intermediate Octreotide 79517-01-4 for Research with GMP
PostPosted: Sat Sep 28, 2019 1:29 am 

Joined: Wed May 08, 2019 3:47 pm
Posts: 411
Pharmaceutical Intermediate Octreotide 79517-01-4 for Research with GMP


English name: Octreotide powder
anothername:L-cysteinamide,D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-(2-hydroxy-1-(hydroxymethyl) propyl)-cyclic (2->7)-disulfide, (R-(R*,R*))
Synonyms:11: PN:US20030229017 PAGE: 13 claimed protein;14: PN: DE10147056 PAGE: 40 claimedprotein;17: PN: US6268342 SEQID: 18 claimed protein;1: PN: EP1118336 SEQID: 1claimed protein;1: PN: WO2005007122 TABLE: 22 claimed protein;25: PN:WO2007081792 SEQID: 40 claimed protein;2: PN: EP1358890 TABLE: A claimedprotein;Longastatin;L-Cysteinamide,D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2
Specification: 98%
CAS NO.: 83150-76-9
Molecular weight:1019.2393
Formula Weight: 1019.24
Molecular formula: C49H66N10O10S2
boilling point:1447.228°C at 760 mmHg
Specification of Octreotide :
1) Purity (HPLC) 98.0%min.
2) Molecular Formula: C49H66N10O10S2
3) Molecular Weight 1019.28
4) Appearance White powder
5) Single Impurity (HPLC) 1.0%max
6) Amino Acid Composition ±10% of theoretical
7) Peptide Content (N%) >80.0%
8) Water Content(Karl Fischer) <7.0%
9) Acetate Content(HPIC) <12.0%
10) Specific Rotation (20/D) -45.0~-50.0°(c=0.5 95%HAc)
11) MS (ESI) Consistent
12) Mass Balance 95.0~105.0%

Approved uses of Octreotide :
The Food and Drug Administration (FDA) has approved the usage of a salt form of this peptide, octreotide acetate, as an injectable depot formulation for the treatment of acromegaly, gigantism, thyrotropinoma, diarrhea and flushing episodes associated with carcinoid syndrome, and diarrhea in patients with vasoactive intestinal peptide-secreting tumors (VIPomas).


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 Post subject: Re: Pharmaceutical Intermediate Octreotide 79517-01-4 for Research with GMP
PostPosted: Thu Jan 09, 2020 10:44 pm 

Joined: Sat Nov 30, 2019 11:41 pm
Posts: 6995
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 Post subject: Re: Pharmaceutical Intermediate Octreotide 79517-01-4 for Research with GMP
PostPosted: Thu Jan 16, 2020 10:32 am 

Joined: Sun Sep 02, 2018 10:06 pm
Posts: 77
this is the empire around the teahouse wine house the most common entertainer.
However, since the empire in recent decades out of several quite famous storytellers, storytellers in various places have caused a stir, the status 10461047 1048 1049 1050 1051 1052 1053 1054 1055 1056 1057 1058 1059 1060 1061 1062 1063 1064 1065 1066 1067 1068 1069 1070 1071 1072 10731074 1075 1076 1077 1078 1079
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1262 1263 1264 1265 1266 1267 1268 1269 1270 storytellers has been significantly improved, the most famous is "east liu west tang, south xie north king" four people. East liu liu zhongyuan, west tang dynasty guo zhong, south thank yi xuan, north wang shifu. Liu zhongyuan mainly activities in the east China sea, jiangnan area, tang guozhong in the river shuo, kansai area walk, xie yixuan is active in the imperial capital, beiyuan, yanyun area, wang shifu to five lakes, three rivers, three counties as the south of the performance area


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